Section on Cell Cycle Regulation (SCCR)

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Welcome to Section on Cell Cycle Regulation

HeLa cells were transfected with RanGAP1-RFP (WT) or RanGAP1-RFP-K524 mutant constructs, and fixed with formaldehyde.

This section studies two closely linked biochemical pathways that are involved in the regulation of mitosis and nuclear trafficking in metazoans: The Ran GTPase pathway and the SUMO-1 conjugation pathway. The goal of our studies is to understand how these pathways contribute to the correct coordination of events during the vertebrate cell cycle.

Section on Cell Cycle Regulation
Laboratory of Gene Regulation and Development
National Institute of Child Health and Human Development
National Institutes of Health
Building 18, Room 106
18 Library Drive, MSC-5431
Bethesda, MD 20892-5431